Modendo Inc.

Harnessing light propagation inside ultrathin fibers to unravel the next endomicroscopes generation.

The University of Colorado Connection

Modendo is developing ultra-thin fiber endoscopes—narrower than a human hair—that enable cellular-resolution imaging (<1 µm) in regions of the body previously inaccessible with conventional tools. These advanced, digitally programmable probes, approximately 100 microns in diameter, contain no moving parts and cause minimal tissue disruption, offering a transformative approach to in-vivo imaging. By reaching deep tissue targets with unprecedented precision and minimal invasiveness, Modendo’s technology addresses critical needs in neuroscience, biomedical research, disease diagnosis and medical treatment.

The company’s foundational technology was pioneered through research led by Rafael Piestun (¾«Æ·SMÔÚÏßӰƬ Electrical, Computer and Energy Engineering) and is based on early innovations in multimode fiber micro-endoscopy and wavefront shaping. Licensed from ¾«Æ·SMÔÚÏßӰƬ, this platform enables real-time, high-resolution image transmission through optical fibers with a cross-sectional area nearly ten times smaller than the thinnest existing endoscopes. Modendo maintains strong ties with the university, including operating an in-vivo imaging lab on campus, and holds issued patents that support its vision of providing safer, more effective imaging alternatives that accelerate recovery and expand the frontiers of medical and scientific exploration.

Funding Status and Investment Opportunities

  • Industry Applications: Hardware and Instrumentation, Health and Wellness, Biotech, Diagnostics, Medical Devices
  • Funding Stage: Pre-Seed
  • Contact for Investment Inquiries: , antonio.caravaca@modendo-inc.com

Technology Development Funding

U.S. National Science Foundation, Colorado Office of Economic Development & International Trade, U.S. National Institutes of Health

U.S. National Science Foundation (NSF), Colorado Office of Economic Development & International Trade (OEDIT), U.S. National Institutes of Health (NIH)


ÌýÌý ÌýThis page was last updated on July 17, 2025. Please email vpnews@colorado.edu for corrections or updates

The Insider Investor E-Newsletter

The InsiderÌýisÌýVenture Partners at ¾«Æ·SMÔÚÏßӰƬ's monthly newsletter featuring theÌýlatest headlines, news, events, opportunities and emerging innovations from the university. We have several editions for our audiences.

Subscribe to The InsiderÌýÌý

Questions about investment opportunities?

Amy Dodenhoff

Amy Dodenhoff · Director of Venture Development

Contact AmyÌý

Media Inquiries

For marketing and communication inquiries, contact Daniel Leonard,Ìýsenior marketing and communications specialist for Venture Partners at ¾«Æ·SMÔÚÏßӰƬ.

For media inquiries, please visit .